Now showing items 1-4 of 4

    • Carrillo, Ileana; Nonato Rabelo, Rayane Aparecida; Barbosa, César; Rates, Mariana; Fuentes Retamal, Sebastián Andrés; González Herrera, Fabiola; Guzmán Rivera, Daniela Inés; Quintero, Helena; Kemmerling Weis, Ulrike; Castillo, Christian; Machado, Fabiana; Díaz Araya, Guillermo; Maya, Juan (Public Library Science, 2021)
      Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and is widely distributed worldwide because of migration. In 30% of cases, after years of infection and in the absence of treatment, ...
    • Fuentes Retamal, Sebastián Andrés (Universidad de Chile, 2015)
      Estudios previos han demostrado que derivados del ácido gálico unidos a trifenilfosfonio mediante una cadena alifática de diez carbonos son efectivos agentes citotóxicos, desacoplando la cadena transportadora de electrones ...
    • Urra Faúndez, Félix Ariel; Fuentes Retamal, Sebastián Andrés; Palominos, Charlotte; Rodríguez Lucart, Yarcely A.; López Torres, Camila Alejandra; Araya Maturana, Ramiro Juan (Frontiers Media SA, 2021)
      The role of metabolism in tumor growth and chemoresistance has received considerable attention, however, the contribution of mitochondrial bioenergetics in migration, invasion, and metastasis is recently being understood. ...
    • Córdova Delgado, Miguel Angel; Fuentes Retamal, Sebastián Andrés; Palominos, Charlotte; López Torres, Camila Alejandra; Guzmán Rivera, Daniela; Ramírez Rodríguez, Oney; Araya Maturana, Ramiro; Urra Faúndez, Félix Ariel (MDPI, 2021)
      Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting proliferation, survival, and metastasis, mitochondria highlight as an important target for anticancer drug discovery. FRI-1, methyl ...